What can you say about vitamin B6 in your ads and on your site?

The library supports 8 wordings for vitamin B6; the strongest is “Supports normal energy-yielding metabolism” (strong, 0.21-100 mg a day). Avoid wording that names or implies a disease, a drug or a treatment, such as “Treats PCOS, or balances hormones in PCOS”.

Also called: Vitamin B-6, Pyridoxine, Pyridoxine HCl, Pyridoxal 5’-phosphate, P-5-P

Reviewed 15 October 2026

Not legal advice. This guide shows the wording that published evidence supports at a daily dose, from the sources linked below; it is not a ruling on any claim. Your own product, its form and dose, and your own evidence still need to match the wording you use.

Supported wordings

What you can say.

Strong evidenceWording 1

Claims Facts

“Supports normal energy-yielding metabolism.”

Daily dose	0.21-100 mg a day
Support	Listed by Health Canada and authorized in the EU after EFSA review.
Dose details	Adults 19 and older. Health Canada: 0.1-100 mg a day (80 mg at 18). EU: at least 0.21 mg, 15% of the 1.4 mg EU reference value (Regulation (EU) No 1169/2011, Annex XIII). ODS upper limit: 100 mg.
Form	Pyridoxine hydrochloride or pyridoxal 5’-phosphate, counted as vitamin B6
Sources	Health Canada monograph: Multi-Vitamin/Mineral Supplements Commission Regulation (EU) No 432/2012, list of permitted health claims

Strong evidenceWording 2

Claims Facts

“Helps form red blood cells.”

Daily dose	0.21-100 mg a day
Support	Listed by Health Canada and authorized in the EU after EFSA review.
Dose details	Adults 19 and older. Health Canada: 0.1-100 mg a day (80 mg at 18). EU: at least 0.21 mg, 15% of the 1.4 mg EU reference value (Regulation (EU) No 1169/2011, Annex XIII). ODS upper limit: 100 mg.
Form	Pyridoxine hydrochloride or pyridoxal 5’-phosphate, counted as vitamin B6
Sources	Health Canada monograph: Multi-Vitamin/Mineral Supplements Commission Regulation (EU) No 432/2012, list of permitted health claims

Strong evidenceWording 3

Claims Facts

“Supports normal function of the nervous system.”

Daily dose	0.21-100 mg a day
Support	Listed by Health Canada and authorized in the EU after EFSA review.
Dose details	Adults 19 and older. Health Canada: 0.1-100 mg a day (80 mg at 18). EU: at least 0.21 mg, 15% of the 1.4 mg EU reference value (Regulation (EU) No 1169/2011, Annex XIII). ODS upper limit: 100 mg.
Form	Pyridoxine hydrochloride or pyridoxal 5’-phosphate, counted as vitamin B6
Sources	Health Canada monograph: Multi-Vitamin/Mineral Supplements Commission Regulation (EU) No 432/2012, list of permitted health claims

Moderate evidenceWording 4

Claims Facts

“Helps regulate hormonal activity.”

Daily dose	at least 0.21 mg a day
Support	Authorized in the EU after EFSA review; Health Canada does not list it.
Dose details	EU: at least 0.21 mg, 15% of the 1.4 mg EU reference value (Regulation (EU) No 1169/2011, Annex XIII). Health Canada does not list this use; its multi-vitamin/mineral monograph gives vitamin B6 at 0.1-100 mg a day for adults. ODS upper limit: 100 mg.
Form	Pyridoxine hydrochloride or pyridoxal 5’-phosphate, counted as vitamin B6
Source	Commission Regulation (EU) No 432/2012, list of permitted health claims

Moderate evidenceWording 5

Claims Facts

“Helps reduce tiredness and fatigue.”

Daily dose	at least 0.21 mg a day
Support	Authorized in the EU after EFSA review; Health Canada does not list it.
Dose details	EU: at least 0.21 mg, 15% of the 1.4 mg EU reference value (Regulation (EU) No 1169/2011, Annex XIII). Health Canada does not list this use; its multi-vitamin/mineral monograph gives vitamin B6 at 0.1-100 mg a day for adults. ODS upper limit: 100 mg.
Form	Pyridoxine hydrochloride or pyridoxal 5’-phosphate, counted as vitamin B6
Source	Commission Regulation (EU) No 432/2012, list of permitted health claims

Moderate evidenceWording 6

Claims Facts

“Supports normal psychological function.”

Daily dose	at least 0.21 mg a day
Support	Authorized in the EU after EFSA review; Health Canada does not list it.
Dose details	EU: at least 0.21 mg, 15% of the 1.4 mg EU reference value (Regulation (EU) No 1169/2011, Annex XIII). Health Canada does not list this use; its multi-vitamin/mineral monograph gives vitamin B6 at 0.1-100 mg a day for adults. ODS upper limit: 100 mg.
Form	Pyridoxine hydrochloride or pyridoxal 5’-phosphate, counted as vitamin B6
Source	Commission Regulation (EU) No 432/2012, list of permitted health claims

Moderate evidenceWording 7

Claims Facts

“Supports normal immune function.”

Daily dose	at least 0.21 mg a day
Support	Authorized in the EU after EFSA review; Health Canada does not list it.
Dose details	EU: at least 0.21 mg, 15% of the 1.4 mg EU reference value (Regulation (EU) No 1169/2011, Annex XIII). Health Canada does not list this use; its multi-vitamin/mineral monograph gives vitamin B6 at 0.1-100 mg a day for adults. ODS upper limit: 100 mg.
Form	Pyridoxine hydrochloride or pyridoxal 5’-phosphate, counted as vitamin B6
Source	Commission Regulation (EU) No 432/2012, list of permitted health claims

Moderate evidenceWording 8

Claims Facts

“Supports normal homocysteine metabolism.”

Daily dose	at least 0.21 mg a day
Support	Authorized in the EU after EFSA review; Health Canada does not list it.
Dose details	EU: at least 0.21 mg, 15% of the 1.4 mg EU reference value (Regulation (EU) No 1169/2011, Annex XIII). Health Canada does not list this use; its multi-vitamin/mineral monograph gives vitamin B6 at 0.1-100 mg a day for adults. ODS upper limit: 100 mg.
Form	Pyridoxine hydrochloride or pyridoxal 5’-phosphate, counted as vitamin B6
Source	Commission Regulation (EU) No 432/2012, list of permitted health claims

How strong the evidence is

Strong evidence: At least two listed sources support it independently at a comparable dose and form, and none disagrees.
Moderate evidence: One listed source supports it as an evidence-based use at that dose, and no listed source disagrees.
Limited evidence: The only support is traditional use, the sources disagree, or the source itself calls the evidence weak.

Wordings to avoid

What to leave out.

Claims Facts

Ingredient: Vitamin B6

Wording to avoid	Reason
“Treats PCOS, or balances hormones in PCOS”Names a disease (polycystic ovary syndrome).	Disease
“Treats PMDD or premenstrual depression”Names medical conditions: premenstrual dysphoric disorder and depression.	Disease
“Treats depression or anxiety”Names diseases.	Disease
“Lowers homocysteine to protect the heart, or reduces the risk of heart disease”Names a disease. FDA’s qualified claim on B vitamins and vascular disease has set wording (see fda_health_claims).	Disease
“Treats carpal tunnel syndrome or nerve damage (neuropathy)”Names diseases.	Disease

Disease: names or implies a disease. Drug: names a drug or presents the product as one. Treatment: promises to treat, cure or prevent a condition.

Sources

Where this comes from.

All ingredient guides

Check the claims on your own site. Free.

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