What can you say about DIM in your ads and on your site?

The library supports 2 wordings for DIM; the strongest is “Helps support healthy estrogen metabolism” (moderate, 60-200 mg a day). Avoid wording that names or implies a disease, a drug or a treatment, such as “Prevents or treats breast, prostate or cervical cancer”.

Also called: 3,3’-Diindolylmethane, Diindolylmethane, 3,3’-Methylenebis-1H-indole

Reviewed 15 October 2026

Not legal advice. This guide shows the wording that published evidence supports at a daily dose, from the sources linked below; it is not a ruling on any claim. Your own product, its form and dose, and your own evidence still need to match the wording you use.

Supported wordings

What you can say.

Moderate evidenceWording 1

Claims Facts

“Helps support healthy estrogen metabolism.”

Daily dose	60-200 mg a day
Support	Health Canada lists it at 60-200 mg a day; no other listed source covers DIM.
Dose details	Adults 18 and older. Health Canada asks for a practitioner’s advice before use, to rule out a serious cause of hormonal imbalance.
Form	3,3’-Diindolylmethane (DIM), isolated or synthetic
Source	Health Canada monograph: 3,3’-Diindolylmethane (DIM)

Limited evidenceWording 2

Claims Facts

“Provides an antioxidant that helps protect cells against damage from free radicals.”

Daily dose	up to 200 mg a day
Support	Health Canada sets a maximum dose only; no other listed source covers it.
Dose details	Adults 18 and older; Health Canada sets a maximum of 200 mg a day.
Form	3,3’-Diindolylmethane (DIM), isolated or synthetic
Source	Health Canada monograph: 3,3’-Diindolylmethane (DIM)

How strong the evidence is

Strong evidence: At least two listed sources support it independently at a comparable dose and form, and none disagrees.
Moderate evidence: One listed source supports it as an evidence-based use at that dose, and no listed source disagrees.
Limited evidence: The only support is traditional use, the sources disagree, or the source itself calls the evidence weak.

Wordings to avoid

What to leave out.

Claims Facts

Ingredient: DIM

Wording to avoid	Reason
“Prevents or treats breast, prostate or cervical cancer”Names diseases; no listed source supports it.	Disease
“Treats estrogen dominance, PCOS or endometriosis”Names or implies hormonal disorders. Health Canada asks for a practitioner’s advice before use, to rule out a serious cause of hormonal imbalance.	Disease
“Blocks estrogen like an aromatase inhibitor or tamoxifen”Compares the product to drugs.	Drug

Disease: names or implies a disease. Drug: names a drug or presents the product as one. Treatment: promises to treat, cure or prevent a condition.

Sources

Where this comes from.

Health Canada monograph: 3,3’-Diindolylmethane (DIM)

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